A young Brooklyn couple heads to an upstate cabin to unplug from their phones and reconnect with each other. Blissfully unaware of their surroundings, they are left to their own devices as the planet falls under attack.

Charles Young (Brian Tyree Henry), a broken-hearted video editor who recently broken up with his girlfriend Isha (Sonequa Martin-Green), sequesters himself at home. But then Charles locks himself out of his apartment, he's forced to meet his previously avoided neighbors, who show him everyone’s got issues and it never helps to keep them all locked up inside.

Set against the world of a major drug cartel bust, the series follows two low-level cops who have spent far too much time in a car together; two criminals who are largely kept in the dark; two dispatch workers who haven't really clicked; and two Mexican tunnelers who are in way too small a space, considering they've only just met.

The Ultra City Smiths story unfolds via the stop-motion animation of baby dolls repurposed as a grown-up cast of characters. The series hinges on an investigation into the mysterious disappearance of fictional metropolis Ultra City's most famous magnate. Two intrepid detectives follow the case, rallying to fight against their city's dangerous corruption, at a high cost to themselves and their families, all in pursuit of a gentler place to call home....